Neuromuscular junction - new formation of NMJ

 

 

The Role of Muscle microRNAs in Repairing the Neuromuscular Junction

Gregorio Valdez,^#1,2,* Mary P. Heyer,^#3,4 Guoping Feng,^3,5 and Joshua R. Sanes¹

Lin Mei, Editor - PLoS One. 2014; 9(3): e93140 - PMCID: PMC3963997

 

“Among the best studied [skeletal muscle fibers] are the subunits of the AChR, which are upregulated by denervation, leading to a phenomenon originally called ‘supersensitivity’.... It is generally presumed that increased density of AChRs in the muscle membrane facilitates formation of new NMJs by regenerating axons”.